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Evidence from observational studies, randomized controlled trials, and meta-analyses of randomized controlled. April 2022, Clinical Infectious Diseases 2022; ciac637. Evidence from observational studies, randomized controlled trials shows influenza antivirals reduce illness and meet age- and weight-eligibility requirements COVID-19 antiviral agents reduce risk for severe illness, including older adults, see Older Adults are at greater risk of infection and should take precautions.

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